Hyperbaric Oxygen Therapy Conditions

Below is a partial list of what is considered “off-label” conditions that have shown to benefit from the use of hyperbaric oxygen therapy. These conditions have not yet received approval from the FDA and Health Canada, but are still showing substantial improvements with hyperbaric oxygen therapy. Click On The Conditions With "Blue" Links For Additional Information. For the full list of conditions approved by the FDA and Health Canada, please scroll down.

Anoxia and Hypoxia:  Near hanging, Birth injury, Smoke inhalation
Autism & Developmental Delays
Cancer immune support
Cerebral Palsy (CP
Crohn's Disease
Cystic Fibrosis
Complex Regional Pain Syndrome (CRPS)

Cosmetic Surgery
Cortical Visual Impairment
Rheumatoid Arthritis
Cranial Nerve Syndromes: Bell's Palsy, Retinal artery occlusion, Trigeminal Neuralgia
Reflex Sympathetic Dystrophy (RSD)
Traumatic Brain Injury (TBI)

Sports Performance Enhancement & Sports Injury
Brown Recluse Spider Bites
Spinal Cord Injury
Fetal Alcohol Syndrome (FAS)
Non-fatal submersion
Pre-and-Post Surgery
Stroke (acute and chronic)
Non-Healing Wounds
Pulmonary Embolism
Skin Conditions
Cerebral edema
Hearing Loss
Irritable Bowel Disease
Multiple Sclerosis  (MS)
Pain Management
Lyme Disease
Retinitis Pigmentosa
Chronic Fatigue
Hypoxic-Ischemic Encephalopathy
Periventricular Leukomalasia
Macular Degeneration
Clostridial myonecrosis
Vegetative coma
Closed Head Injuries
Memory Loss
Migraines/Cluster Headaches

Off-Label refers to the use of hyperbaric oxygen therapy for treatment indications that have not yet been approved by the FDA/Health Canada for marketing purposes. The FDA and Health Canada play a significant role in how hyperbaric oxygen therapy is used; from the type of hyperbaric machines to the indications/conditions approved

An indication will generally only receive approval by the FDA and Health Canada after it has passed rigorous studies, which include double blind studies that demonstrate a quantifiable degree of improvement in a specific condition.

The cost to conduct studies that would satisfy these governing bodies would cost millions of dollars. Dues to the fact that oxygen cannot be patented, profits made from the sale of oxygen are too small to pay for studies that would meet the FDA and Health Canada’s requirements.

The International Hyperbaric Medical Associations position on the “off-label” use of hyperbaric oxygen therapy treatments. http://www.therapiehyperbare.com/en/ihma_position_off-label_hbot.html

Health Canada and The FDA Recognizes Hyperbaric Oxygen Therapy for the Following Conditions:

Air or Gas Embolism

An air embolism, or more generally gas embolism, is a physiological condition caused by gas bubbles in a vascular system. The most common context is a human body, in which case it refers to gas bubbles in the bloodstream (embolism in a medical context refers to any large moving mass or defect in the blood stream). However air embolisms may also occur in the xylem of vascular plants, especially when suffering from water stress.

Carbon Monoxide Poisoning

Carbon monoxide poisoning occurs after the inhalation of carbon monoxide (CO). Carbon monoxide is a significantly toxic gas, but, being colorless, odorless, tasteless, and non-irritating, it is very difficult for people to detect. Carbon monoxide is a product of combustion of organic matter with insufficient oxygen supply and is often produced in domestic or industrial settings by motor vehicles and other gasoline-powered tools, heaters, and cooking equipment.

Clostridal Myositis and Myonecrosis (Gas Gangrene)

Myonecrosis is a condition of necrotic damage, specifically to muscle tissue. It is often seen in infections with Clostridium perfringens or any of myriad soil-borne anaerobic bacteria. Bacteria cause myonecrosis via specific exotoxins. These microorganisms are opportunistic and generally enter the body via significant skin breakage. In wartime particularly, the unhygienic conditions and frequent gross injuries meant that gangrenous infection of soil-borne bacteria was particularly prevalent. Indeed mankind has long suffered the ill-effects of gangrenous infections throughout history.

Crush Injury, Compartment Syndrome, and other Acute Traumatic Ischemias

Compartment syndrome is an acute medical problem following injury, surgery or in most cases repetitive and extensive muscle use, in which increased pressure (usually caused by inflammation) within a confined space (fascial compartment) in the body impairs blood supply. Without prompt surgical treatment, it may lead to nerve damage and muscle death. This condition is most commonly seen in the anterior compartment and posterior compartment of the leg.

Decompression Sickness

Describes a condition arising from the precipitation of dissolved gasses into bubbles inside the body on depressurisation. DCS most commonly refers to a specific type of scuba diving hazard but may be experienced in other depressurisation events such as caisson working, flying in unpressurised aircraft and extra-vehicular activity from spacecraft.

Enhancement of Healing in Selected Problem Wounds

A wound that does not heal in an orderly set of stages and in a predictable amount of time the way most wounds do; wounds that do not heal within three months are often considered chronic. Chronic wounds seem to be detained in one or more of the phases of wound healing. Chronic wounds may never heal or may take years to do so. These wounds cause patients severe emotional and physical stress as well as creating a significant financial burden on patients and the whole healthcare system.

Exceptional Blood Loss (Anemia)

Anemia is the most common disorder of the blood. There are several kinds of anemia, produced by a variety of underlying causes. Since hemoglobin (found inside RBCs) normally carries oxygen from the lungs to the tissues, anemia leads to hypoxia (lack of oxygen) in organs. Since all human cells depend on oxygen for survival, varying degrees of anemia can have a wide range of clinical consequences.

Intracranial Abscess

is an abscess caused by inflammation and collection of infected material, coming from local (ear infection, dental abscess, infection of paranasal sinuses, infection of the mastoid air cells of the temporal bone, epidural abscess) or remote (lung, heart, kidney etc.) infectious sources, within the brain tissue. The infection may also be introduced through a skull fracture following a head trauma or surgical procedures.

Necrotizing Soft Tissue Infections

Are commensal organisms in humans, living predominantly in the mouth, skin, gastrointestinal, and urinary tracts, and compose a portion of the bacterial gut flora. Under immunosuppressed or traumatic conditions these organisms can become pathogenic, as well as septicemic, harming their host. Necrotizing infections can cause brain, liver, breast, and lung abscesses, as well as generalized necrotizing soft tissue infections.

Osteomyelitis (Refractory)

An infection of bone or bone marrow with a propensity for progression.

Delayed Radiation Injury (Soft Tissue and Bony Necrosis)

A form of damage to organ tissue due to excessive exposure to ionizing radiation. Radiation exposure can also increase the probability of contracting some other diseases, mainly cancer, tumours, and genetic damage.

Skin Grafts & Flaps (Compromised)

A type of medical grafting involving the transplantation of skin. Extensive wounding or trauma, Burns, Areas of prior infection with extensive skin loss and Specific surgeries that may require skin grafts for healing to occur.

Thermal Burns

Thermal burns are the most common type. Thermal burns occur when hot metals, scalding liquids, steam, or flames come in contact with your skin. These are frequently the result of fires, automobile accidents, playing with matches, improperly stored gasoline, space heaters, and electrical malfunctions.